I once developed a "fan fiction RPG" based on Alpha Centauri, the computer game. The players had landed in a United Nations Unity Pod, and developed their first city by taking apart the pod. This was UN Headquarters. Later, three other colonies were made nearby -- mostly lower population agricultural societies. Each one had different local laws, but they all answered to UN Headquarters. Roads were made from each colony, to each colony.
Sensor towers were erected to keep an eye on the colonies and surrounding territories, but there's not enough sensor towers for the outlying regions. The three outer colonies can't even keep the power on all the time, and the competition for limited resources granted by UN Headquarters means a great deal of political strife and rivalry. The roads are dangerous and so are frequently patrolled by UN Peacekeepers. There's plenty of land to grow food, but farming is one of the most dangerous occupations because it means you're pretty much on your own and there's so many health risks that local media outlets have started to report corruption among food inspectors, doctors, and other government officials.
Despite all these human problems, the PCs spent most of their time away from the colony. They were UN Rangers, and their task was to explore the nearby terrain and gather information, build maps, and report back about dangers or resources that they found. Over the course of their travels, they discovered fungal blooms, ways to harness the fungus for medicinal purposes, giant fungal towers... and the omnipresent threat of Mindworm Boils. Their ultimate goal was to find crashed debris from the original Unity starship, and recover any tech or data they found.
In one adventure, they found a pod that had a manifest of three exploration vehicles, and thought they had hit the motherload only to discover it had been opened and looted. This is when they realized their escape pod wasn't the only one that escape the crashing starship and they set out to find other signs of human survival. This eventually led them into conflict with a group of religious fanatics calling themselves the Believers, and the campaign started to become more political and military oriented after that.
I've looked for my notes on that setting, as I had some details on politics, economy, law, technology, etc, but I can't find it right now. If I find it, I'll post it, and you can use whatever you like.