I'd say no. Having a PC retire with allies seems like it would stabilize those allies even further, maybe even to the point of moving them off-screen entirely. "Yeah, didn't [Skinner] and her pals take up gardening/ get really into their little family/ head out west a few years back? She used to be badass, but now they just keep to themselves. Stil, I wouldn't mess with them. Sometimes they're good for a quick meal or some intel."